Naam
Naamdr. SA Shetty
RoepnaamSudarshan
Emailsudarshan.shetty@wur.nl

Werk
OmschrijvingOnderzoeker
OrganisatieDepartement Agrotechnologie en Voedingswetenschappen
OrganisatieeenheidMicrobiologie

Expertiseprofiel
Expertise
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  Sudarshan Shetty op Linkedin
  Sudarshan Shetty op ResearchGate
  Sudarshan Shetty op Twitter

Publicaties
Kernpublicaties
Publicatielijsten

Projecten

Ecophysiological insights into the human intestinal microbiota

The human intestinal tract consists of trillions of microbes. These microbes have a profound influence on our health. How do more than 1000 bacterial species co-exist in a dense ecosystem is not well known. We also do not have in-depth understanding of the metabolic interactions that occur between the competing and complimenting species. Studying them in their natural ecosystem is technically challenging. We have designed a minimal microbiome that mimics key ecological and metabolic properties of the human microbiome. The minimal microbiome consists of important intestinal microbiota that we identified using publicly available metagenomics datasets. We are currently studying the in-vitro compositional dynamics of the minimal microbiome and furhter we are investigating their functional dynamics using multi-omics as well as basic microbiological assays.

Tools for microbial community analysis

We have developed tools alongwith Dr. Leo Lahti from Open research labs University of Turku for microbial community analysis.

Microbiome R/BioC package tutorials [http://microbiome.github.io/microbiome/]

Microbiomeutilities R package[https://microsud.github.io/microbiomeutilities/articles/microbiomeutilities.html]

Further reading

Shetty SA, et al. 2017: Intestinal microbiome landscaping: insight in community assemblage and implications for microbial modulation strategies.

For more information contact: Sudarshan A. Shetty; sudarshan.shetty@wur.nl


Onderwijs

MSc (Microbiology), University of Pune, India

Ph.D. Laboratory of Microbiology, Wageningen University and Research

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