Sensitivity of rainbow trout (Oncorhynchus mykiss) to mycotoxins.
Mycotoxins are toxic secondary metabolites produced by moulds, mainly found on agricultural commodities and produced before and/ or after harvest; during transportation or storage. Mycotoxins are a rising-threat on aquaculture industry since the probability of contamination in aquafeed has been enhanced due to the climate change and the increased use of risky/contaminated ingredient (plant ingredients, by-products). In animals including fish, ingestion of mycotoxin-contaminated feeds has been associated with organ failure, carcinogenicity, neurotoxicity, immune suppression, reproductive and developmental toxicity. Several studies have been investigated the single effect of mycotoxins on fish species, although numerous mycotoxins usually contaminate feeds. Mycotoxin co-occurrence might have synergetic effects that increase the negative impacts of mycotoxins, but these derived impacts are still not well determined. A potential strategy for reducing the animal exposure to mycotoxins is to minimise their availability by the addition of various mycotoxin-binding agents or absorbents to the feed.
The project aims at better understanding the effects of single mycotoxins as well as multiple mycotoxins on rainbow trout and evaluating the role of a specific mycotoxin binder as a potential treatment.
Finally, the societal impact of the project is to contribute to more a sustainable aquaculture production, by improving animal welfare and health, and improved return on investment in the sector.