Naam
Naam A Alekseeva PhD
RoepnaamAnna
Emailanna.alekseeva@wur.nl

Werk
OmschrijvingExterne medewerker
OrganisatieDepartement Plantenwetenschappen
OrganisatieeenheidLaboratorium voor Erfelijkheidsleer
Reguliere werkdagen
Ma Di Wo Do Vr
Ochtend
Middag

Expertiseprofiel
Expertise

Publicaties
Kernpublicaties

Projecten

Linking species diversity to microbial ecosystem functionality

There is a tremendous variation among natural ecosystems in the diversity of species and their interactions, which are thought to define ecosystem stability and functionality. Ecological theory predicts that the stability of an ecosystem relies on balanced interspecies interactions and how these species interact with the environment. Here, we propose a popular Zambian fermented product, Mabisi, as a model system to study what mechanisms drive the community stability. In contrast to most other natural ecosystems, Mabisi harbours a relatively simple microbial community of six to eight most abundant species of bacteria and yeasts. Such a low taxonomic diversity allows us to experimentally test whether species composition, type of interspecies interactions, environmental conditions, and degree of long-term co-existence define stability of the community. We intend to link the functionality of individual species to ecosystem stability and build a model of the microbial community interactions. Our work will also allow us to design stable starter cultures for safe and sustainable production of Mabisi and other traditional fermented milk products.


Onderwijs

2004 – 2009, Lomonosov Moscow State University, Faculty of Biology, Moscow, Russia: University specialist degree (equivalent to MSc) in human and animal physiology. 4th-5th year diploma project in Physiology, Cell Biology and Immunology.

2010 – 2014 PhD researcher at the Laboratory of Molecular Biology, Moscow, Russia. Obtained a PhD in cell biology and genetics.

Improved the understanding of immunological effects of circulating DNA on molecular pathways in various cells. Revealed variations in gene and protein expression profiles during stress, immune response and apoptosis signal transduction in cancer cells, lymphocytes, HUVECs and MSCs. Ascertained the cytotoxic effects of circulating DNA on human cells.

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