CarboBiotics: improving resilience after exposure to antibiotics

Antibiotics are efficient against infectious diseases. However, they can also have detrimental effects on the gut microbiota and its resilience, depending on the type of antibiotics as well as the individual microbiota composition. This project will study mechanisms underlying the individual-specific level of resilience after antibiotics exposure and whether fast recovery can be induced by specific non-digestible carbohydrates.

CarboBiotics Programme

This project is part of the NWO-CCC Partnership Programme “CarboBiotics: Pre/Probiotics mitigating the Antibiotics burden”.

Previous study

Reijnders, D. et al. Effects of gut microbiota manipulation by antibiotics on host metabolism in obese humans: a randomized double-blind placebo-controlled trial. Cell Metab. 24, 63–74 (2016). DOI: https://doi.org/10.1016/j.cmet.2016.06.016