Prof. Paul Carmichael has worked in the Safety & Environmental Assurance Centre (SEAC) of Unilever in the UK since 2004, where he is responsible for the development and implementation of novel non-animal-based approaches for assuring human and environmental health; that is to say, how can consumer and environmental safety be assured without using and harming animals? He has over thirty years’ experience in toxicology and cancer research, largely in the academic arena, and prior to Unilever, he was a Senior Lecturer at Imperial College London in the Faculty of Medicine, where he taught pharmacology and toxicology and conducted research into advances in toxicology. A graduate of Surrey University with a B.Sc. in Biochemistry/Toxicology and a Ph.D. from King’s College London, he was a postdoctoral scientist at the Institute of Cancer Research (Royal Marsden Hospital) for seven years, exploring mechanisms of chemical genotoxicity and carcinogenicity. He currently has close academic links with Peking University in China (the School of Public Health) and is an Adjunct Assistant Professor of Pathology and Laboratory Medicine at Brown University in the USA, where he lectures annually and mentors students. He was appointed an Endowed Professor of Next Generation Risk Assessment Approaches for Human and Environmental Health at Wageningen University (WUR) in the Netherlands in 2020. He has published over one hundred research papers in peer-reviewed scientific journals and has served or serves on many committees in the UK, US, EU and China. His passion is the advancement of new safety assessment approaches using the inspiration of ‘Toxicity Testing in the 21st Century’ and his vision for the Special Professorship at WUR is to explore the utility of new approach methodologies (NAMs) in the risk assessment of novel ingredients intended for foods and consumer products.