Search staff/organisations prof. M Srinivas
Name
Nameprof. M Srinivas
FirstnameMangala
Emailmangala.srinivas@wur.nl

Job details
DescriptionProfessor/Chairholder
OrganizationDepartment of Animal Sciences
Organization UnitCell Biology and Immunology
Phone
Mobile
Secretarial phone+31 317 483 922
Phone 2
Fax
Note for telephonist
Note by telephonist
Visiting addressDe Elst 1
6708WD, WAGENINGEN
Building/Room122/E1260
Postal addressPostbus 338
6700AH, WAGENINGEN
Courier142
Regular availability
Mo Tu We Th Fr
Morning
Afternoon
Ancillary activities
  • ZonMW Open Competition review committee - ZonMW
    Oct 2021 - Present

    Grant review committee

  • - Cenya Imaging BV
    May 2021 - Present

    Employment at spin-off company, focusing on GMP-grade nanoparticles for imaging. Possible conflicts of interest with my work at WUR have been discussed. All work at WUR will remain confidential.

  • International Expert Panel (3-year term, inter-disciplinary - Flanders Research Foundation (FWO)
    Apr 2021 - Apr 2024

    Review board for various grants, at least 2x a year.


Biography

Mangala has (May 2021) started as Professor and Chair Group Leader at Wageningen University & Research, in Cell Biology and Immunology (CBI). Her group is currently in a transition phase. She will continue as CSO of Cenya Imaging BV.

Mangala started her career in research at the National University of Singapore, before completing her Ph.D. at Carnegie Mellon University (USA). She is the founder and CSO of Cenya Imaging, a spin-off from her academic group at the Radboud University Medical Center in Nijmegen, the Netherlands. Her work focuses on agents for in vivo imaging. Mangala's early work helped establish the field of 19F MRI for quantitative in vivo cell tracking. More recently, her group works on customisable nanoparticles for imaging and advanced personalised medicine applications, such as cell therapies. Some of these nanoparticles are produced at GMP-grade for a clinical cell tracking study using multimodal imaging, in melanoma patients. Her group works with fluorescence, MRI, PET, SPECT, ultrasound and photoacoustic imaging in different­ disease models, particularly cancer and cardiovascular disease. This multidisciplinary work is, and has been, supported by prestigious grants such as an NWO VENI, ERC Starting Grant (the largest European grant available to early stage researchers), ERA-NET CVD grant, 3 ERC PoCs, and others. She won the Dutch Venture Challenge in 2015, for her ideas on cell tracking.

Overall, Mangala’s team has taken a new type of imaging agent from development to the clinic and commercialisation.

Mangala is also active in the Young Academy of Europe (YAE), where she served as Chair for two full terms; she also served as Category Chair for the European Molecular Imaging Meetings, twice. Mangala was also shortlisted for the World Molecular Imaging Society WIMIN Outstanding Leadership award in 2019.

In addition to her academic career, Mangala worked for GE Healthcare in Strategy, Search and Evaluation, where she helped identify and evaluate emerging technologies in the fields of imaging.

Mangala has given many invited talks and been on panels, such as at the International Society for Magnetic Resonance in Medicine, CATAPULT UK, Phacilitate Cell and Gene Therapy, European Infrastructure for Translational Medicine (EATRIS), and WMIC. She has also been invited to several meetings, such as by the International Science Council, the Association of Universities in the Netherlands (VSNU), European University Association (EUA), and UNESCO.

At home, Mangala, has 3 children, all under the age of 10. You may see and probably will hear them in the background at some video calls.


Expert Profile
Expertise
Social media
  Mangala Srinivas on Linkedin

Publications
Publication lists
Researcher ID's

Projects

Strijkers G, Vandoorne K, Srinivas M. Fluorine magnetic resonance and ultrasound imaging of cardiac inflammation (MUSICIAN). STW grant, NWO Technology Foundation (€750, 000). 2016-’21.

Srinivas M. Junior Principal Investigator status at Radboud UMC. This is a competitive grant with requirements in publications, successful grants and social standing (€57,500 per year).  

Benzton JF, Feil S, Srinivas M. SCAN: Subclinical atherosclerosis characterization: Nanoparticle-based molecular and cellular imaging. ERA-NET CVD (€800, 000).  2018-2021.

Srinivas M, Simon J. Multimodal imaging agents for cell tracking. Radboud Innovation Fund (€80k).

Srinivas M. EU Nanoparticle Characterisation Lab (EU NCL) for full characterisation of the particles, including in vivo toxicity testing.

Srinivas M, Simon J. Multimodal imaging contrast agents. NWO Take-off Phase 1 (€40, 000).

Srinivas M, Simon J. Cenya. ERC Proof of Concept (€150, 000). 2019-2021.

Srinivas M, Simon J. Cenya Imaging. RedMedTech (€250, 000). 2019-2024.

Srinivas M, Simon J. Cenya Imaging. NWO Take-off Phase II (€250,000). 2019-2024.

Srinivas M and consortium (coordinated by LeidenUMC). NOVA-MRI: Novel applications in 19F MRI. H2020-MSCA-ITN-2019 (€4.05M; about 500k to Cenya). 2019-2024.

Srinivas M, and consortium (coordinated by VILABS, Greece). CALIPER: Linking research and innovation for gender equality. H2020-SwafS-2019-1 (€2.9M; 158k to YAE). 2019-2024.

Srinivas M, and consortium. COST Cross-Cutting Activity. How to address the increasing challenge of science communication in a diverse European (media) landscape? (YAE) 2019-2022.

Srinivas M, Simon J (Cenya), Mondino A & Chaabane L (San Raffaele), Debet R & Bernsen M (ErasmusMC), Maynard J (Medicines Discovery Catapult UK). Translatable multimodal imaging agent for tracking and quantifying cell therapies in vivo. CRACK IT Challenge Phase 1 by Innovate UK, together with GSK and Novartis (£100k, for 6 months). 2020.

Srinivas M, and consortium (coordinated by MJR-PharmJet. Pharmaceutical Open Innovation Test Bed for Enabling Nano-pharmaceutical Innovative Products (PHOENIX). H2020-NMBP-TO-IND-2020-twostage call (€14.45M). 2021-2025.

Srinivas M. Intraveneously injected unusual nanoparticles in the clinic (Unusual-IV). ERC Proof of Concept (€150, 000). 2021-2022.

 


Education
Courses
  • CBI21303 - Basics of Immunotechnology
  • CBI70224 - MSc Internship Cell Biology and Immunology
  • CBI70424 - MSc Internship Cell Biology and Immunology
  • CBI79224 - MSc Research Practice Cell Biology and Immunology
  • CBI79324 - MSc Research Practice Cell Biology and Immunology
  • CBI80424 - MSc Thesis Cell Biology and Immunology
  • CBI80436 - MSc Thesis Cell Biology and Immunology
  • YBT80324 - BSc Thesis Biotechnology
  • YNH80312 - BSc Thesis Nutrition and Health
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